| Driver | GP | Tyres | From | To | #Laps |
|---|---|---|---|---|---|
| Max Verstappen | United States | Medium New | 1 | 13 | 13 |
| Max Verstappen | United States | Hard New | 14 | 35 | 22 |
| Max Verstappen | United States | Medium New | 36 | 56 | 21 |
| Lewis Hamilton | United States | Medium New | 1 | 12 | 12 |
| Lewis Hamilton | United States | Hard New | 13 | 34 | 22 |
| Lewis Hamilton | United States | Hard New | 35 | 56 | 22 |
| Charles Leclerc | United States | Medium New | 1 | 18 | 18 |
| Charles Leclerc | United States | Hard New | 19 | 35 | 17 |
| Charles Leclerc | United States | Medium New | 36 | 56 | 21 |
| George Russell | United States | Medium New | 1 | 13 | 13 |
| George Russell | United States | Hard New | 14 | 36 | 23 |
| George Russell | United States | Hard New | 37 | 54 | 18 |
| George Russell | United States | Soft Used | 55 | 56 | 2 |
| Lando Norris | United States | Medium New | 1 | 14 | 14 |
| Lando Norris | United States | Hard New | 35 | 56 | 22 |
| Lando Norris | United States | Hard New | 15 | 34 | 20 |
| Fernando Alonso | United States | Medium New | 19 | 22 | 4 |
| Fernando Alonso | United States | Hard New | 23 | 56 | 34 |
| Sebastian Vettel | United States | Medium Used | 1 | 18 | 18 |
| Sebastian Vettel | United States | Medium Used | 19 | 41 | 23 |
| Sebastian Vettel | United States | Hard Used | 42 | 56 | 15 |
| Fernando Alonso | United States | Hard New | 1 | 18 | 18 |
| Kevin Magnussen | United States | Hard New | 1 | 18 | 18 |
| Kevin Magnussen | United States | Medium New | 19 | 56 | 38 |
| Yuki Tsunoda | United States | Medium New | 1 | 10 | 10 |
| Yuki Tsunoda | United States | Medium New | 11 | 33 | 23 |
| Yuki Tsunoda | United States | Hard New | 34 | 56 | 23 |
| Esteban Ocon | United States | Hard New | 1 | 18 | 18 |
| Esteban Ocon | United States | Hard New | 19 | 45 | 27 |
| Esteban Ocon | United States | Medium New | 46 | 56 | 11 |
| Alexander Albon | United States | Medium New | 1 | 9 | 9 |
| Alexander Albon | United States | Medium New | 10 | 18 | 9 |
| Alexander Albon | United States | Hard New | 19 | 56 | 38 |
| Zhou Guanyu | United States | Medium New | 1 | 8 | 8 |
| Zhou Guanyu | United States | Hard New | 24 | 56 | 33 |
| Pierre Gasly | United States | Medium New | 1 | 11 | 11 |
| Pierre Gasly | United States | Hard Used | 12 | 32 | 21 |
| Pierre Gasly | United States | Hard Used | 33 | 56 | 24 |
| Mick Schumacher | United States | Hard New | 1 | 18 | 18 |
| Mick Schumacher | United States | Medium New | 19 | 33 | 15 |
| Mick Schumacher | United States | Hard New | 34 | 56 | 23 |
| Daniel Ricciardo | United States | Medium New | 1 | 10 | 10 |
| Daniel Ricciardo | United States | Hard New | 11 | 35 | 25 |
| Daniel Ricciardo | United States | Medium New | 36 | 56 | 21 |
| Nicholas Latifi | United States | Medium New | 1 | 5 | 5 |
| Nicholas Latifi | United States | Medium New | 6 | 18 | 13 |
| Nicholas Latifi | United States | Hard New | 19 | 56 | 38 |
| Lance Stroll | United States | Medium Used | 1 | 15 | 15 |
| Lance Stroll | United States | Medium Used | 16 | 21 | 6 |
| Valtteri Bottas | United States | Medium New | 1 | 10 | 10 |
| Valtteri Bottas | United States | Hard New | 11 | 16 | 6 |
| Carlos Sainz | United States | Medium New | 1 | 1 | 1 |
| Sergio Perez | United States | Medium New | 1 | 14 | 14 |
| Sergio Perez | United States | Hard New | 15 | 38 | 24 |
| Sergio Perez | United States | Medium New | 39 | 56 | 18 |
| Zhou Guanyu | United States | Hard New | 9 | 23 | 15 |